Endocrine Abstracts

Introduction and aim: Diabetic foot (DF) is associated with increased morbimortality and cost of diabetes management. The aim of this study is to describe the epidemiological, clinical and paraclinical characteristics and follow-up outcomes of patients with diabetic foot in a Tunisian center.Methods: It is a monocentric retrospective study of 210 patients with diabetic foot followed at the endocrinology department of the Hedi Chaker Sfax University Hospi...

Introduction: Berberis vulgaris is a plant, of the family Berberidaceae. Berberine is the main active compound of the barberry. It is an iso quinoline alkaloid of intense yellow color. Berberis vulgaris is used in several medical purposes, including liver protection, anti-oxidant, antimicrobial agent. It also seems to reduce the level of cholesterol in the blood and triglycerides. Our study aims to investigate the effect of the dietary supplement "Berberis Vulgaris" ma...

Introduction: Pancreatic cancer is one of the digestive system cancers whose prognosis has not been improved, both in terms of early diagnosis and prognosis, despite the progress in clinical, radiological and biological investigation. A significant number of patients present at the time of diagnosis of this cancer, or just before, a relatively recent onset diabetes. The link between diabetes and pancreatic cancer is established, but it is sometimes difficult to distinguish whe...

Introduction: Obesity, through its complications, influences the functional and vital prognosis. The search for these complications constitutes a major axis of the management of the obese patient, independently of the weight loss. The objective of this work is to focus on the different complications of obesity and to identify, through a comparative study between two groups of obese patients, complicated versus uncomplicated, the different predictive factors of the occurrence o...

Introduction: Gonadal tumors are rare in children. Because surgery is the primary treatment for ovarian tumors, ovarian salvage with fertility preservation and use of a minimally invasive surgical technique are important in children and adolescents. We report the case of an adolescent girl who was referred after bilateral annexectomy. Observation: This is a 14-year-old girl who just had her first menses. She has been followed the last year for an ovarian...

Introduction: Multiple endocrine neoplasia type 2 (MEN2) is a rare inherited disease characterized by the occurrence of medullary thyroid cancer (MTC) either isolated or associated with pheochromocytoma, primary hyperparathyroidism (PHP), or typical morphological features. Thus, we report two cases.Patient(1): A 27-year-old female patient with a marfanoid appearance, had a histologically confirmed conjunctival and mucosal ganglioneuromatosis, bilateral c...

Introduction: Insulinoma is a rare pancreatic tumor. It is the most frequent cause of organic hypoglycemia due to endogenous hyperinsulinism.Case report: A 55-year-old woman was admitted in our department for the management of a recurrent hypoglycemic coma. Endogenous hyperinsulinic hypoglycemia was confirmed with a spontaneous hypoglycemia. Plasma blood glucose was 0.25 g/l concomitant to a high insulinemia of 31.5 µUI/ml (≥ 3) and C-peptide ...

Introduction: Giant prolactinomas (GP), defined as prolactinomas ≥4 cm in maximum dimension, are uncommon, with reported prevalence of 2 to 3% of all prolactinomas. Aim: The aim of this study is to describe clinical and paraclinical characteristics of GP and to identify predictors of therapeutic response.Matherials and methods: A retrospective, single-center, descriptive study including 18 patients with GP followed at the end...

Introduction: The nephrogenic diabetes insipidus (DI) is an entity to be known. It is essential to know its etiologies and especially its therapeutic modalities which are different from those of the central DI. The familial nature of the disease should suggest a genetic origin. In our paper, we are presenting the case of a Tunisian family with genetic nephrogenic DI.Case reports: Our family had a history of neglected polyuro-polydipsic syndrome (PPS), de...

Introduction: Tuberculosis is an infectious disease that involves any organ. However, the primary pituitary tuberculosis is an extremely rare disease. Intracranial tuberculomas account for 0,15-5% of intracranial space-occupying lesions, of which pituitary as the primary site, and easily misdiagnosed as pituitary adenoma. In this setting, the late diagnosis can result in permanent endocrine dysfunction. We hereby report the case of a patient with pituita...